Licensed to kill.

Licensed to Kill: Towards Natural Killer Cell Immunotherapy

Islet autoreactive CD8 T-cells in type 1 diabetes: licensed to kill?

While differentiating T-cell autoreactivity against pancreatic islets between type 1 diabetic patients and nondiabetic control subjects has, over time, proven to be a difficult task, the ultimate challenge for cellular markers of this disease will involve the definition of immunological measures associated with disease progression and intervention. With the notion that type 1 diabetes is a T-ce...

Inflammatory Monocytes and Neutrophils Are Licensed to Kill during Memory Responses In Vivo

Immunological memory is a hallmark of B and T lymphocytes that have undergone a previous encounter with a given antigen. It is assumed that memory cells mediate better protection of the host upon re-infection because of improved effector functions such as antibody production, cytotoxic activity and cytokine secretion. In contrast to cells of the adaptive immune system, innate immune cells are b...

Die to kill: psychological and sociological study of suicide terrorism

One of the principal challenges now days, especially in the countries which are engaged in inland riots, is suicide attack which spreads fear broadly in human societies. More than the legal and political reactions to this social phenomenon, one of the preventive ways, is to analyze the suicide terrorists personally. No doubt, achievement to this understanding can be influential in preventing th...

DNA vaccines and apoptosis: to kill or not to kill?

The Journal of Clinical Investigation | July 2003 | Volume 112 | Number 1 RNase. Proc. Natl. Acad. Sci. U. S. A. 100:4102-4107. 14. Shinkura, R., et al. 2003. The influence of transcriptional orientation on endogenous switch region function. Nat. Immunol. 4:435–441. 15. Yu, K., Chedin, F., Hsieh, C.L., Wilson, T.E., and Lieber, M.R. 2003. R-loops at immunoglobulin class switch regions in the ch...